Chelsea will be without midfielder Deco for Saturday's Premier League home match with Everton at Stamford Bridge.
Deco misses out because his father is ill and defender Alex (thigh) and Salomon Kalou (thigh) are also sidelined.
However, both Alex and Kalou are expected to be fit for the home match with Portsmouth next week. Jose Bosingwa is out with a long-term knee injury.
Coach Carlo Ancelotti will recall Petr Cech, Branislav Ivanovic, Ashley Cole, Michael Ballack, Frank Lampard and Nicolas Anelka after resting them for the midweek Champions League match against APOEL.
Midfielder Tim Cahill is suspended. The Australia international accumulated his fifth booking of the season in last weekend's 2-2 draw with Tottenham Hotspur and so must serve a one-match ban.
Manager David Moyes still has defensive problems with centre-half Joseph Yobo ruled out for four weeks with a hamstring problem.
That means full-back Tony Hibbert is likely to continue to deputise alongside Johnny Heitinga, who returns after suspension.
Chelsea: Cech, Hilario, Turnbull, Ivanovic, Belletti, Carvalho, Terry, A Cole, Lampard, Ballack, Obi, Malouda, J Cole, Zhirkov, Drogba, Anelka, Kakuta, Bruma, Borini.
Everton: Howard, Yobo, Baines, Hibbert, Cahill, Gosling, Rodwell, Bilyaletdinov, Fellaini, Pienaar, Saha, Yakubu, Neill, Nash, Jo, Baxter, Agard, Wallace, Duffy, Coleman.
